Tissue Regenix Grp Live Discussion

marktime1231 02 Feb 2020

Interesting RNS OK this is not my area but I think what this means is … US FDA banning synthetic mesh as an option for prolapse repair. A conclusion reached by UK NICE last year, I think about 10,000 a year in the UK. The alternatives in serious cases are native tissue repair so surgery to repair and maybe using part of the patients own tissue not always very effective; and / or an insert-grafting type treatment using TRXs DermaPure technology I think a bit like stem cell implant in a special framework to encourage the patient to regenerate their own tissue. Already available in private US medical practice and this sounds like an extended trial, so potentially good for TRX business in the US. Not sure what the position of NICE re NHS is, but for sure a better solution than synthetic mesh will be needed here too. Might not pass our affordability tests. The problem is not, however, with TRX technology, I am sure it is great stuff and should be a winner in the right hands. The problem is not even with scale necessarily, it is with TRX operational and financial management … someone more competent at the commercial production engineering of specialist biotech needs to step in and find a way of exploiting TRXs ip, and not p off the investment bank.

trump53 31 Jan 2020

Interesting RNS Hi chaps, I usually follow LSE more than ii. As I had not seen these stories appear on this board, I wanted to make sure you aware of them: Clinical Trial: The investigator is comparing FDA-approved DermaPure with patient’s own native tissue for the repair of pelvic organ prolapse.23.01.2020 clinicaltrials.gov Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse -... Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse - Full Text View. +++++ 17.04.2019 FDA Halts Sale of Transvaginal Surgical Mesh Tied to Patient Lawsuits Xtalks – 17 Apr 19 FDA Halts Sale of Transvaginal Surgical Mesh Tied to Patient Lawsuits Read more about why the FDA determined that two manufacturers haven't shown reasonable assurance of safety, effectiveness for transvaginal surgical mesh. +++++ U.S. Food and Drug Administration – 9 Nov 19 FDA takes action to protect women’s health, orders manufacturers of surgical... FDA informs companies that the agency is not approving their PMA applications and that they will have to remove their products from the market

theprior 22 Jan 2020

Interesting RNS Can’t disagree Mark, but I tend to be glass half full on this one. True the demand profile has softened but, remember, they added that second shift in q4/19 to meet the demand so , not unexpected. As product reach grows, so will demand. Still say today’s drop is over exaggerated. It will come back, just have to wait and see how the next quarter goes Luck all, TP

marktime1231 22 Jan 2020

Interesting RNS The surprise in this announcement is not that the operating performance and cash burn horizon is no better or worse, but that they had to lay off 18 staff just before Christmas presumably under pressure from MidCap Finance. Profitability is way off still then, I’m guessing a loss for the year of about £7M, and the outlook is no more promising, the strategy of adding capacity to meet demand has been softened to “expected demand”. No progress on refinancing nor putting permanent executive in charge. And yet the technology is proven and commercial eg £13M sales, albeit unprofitable. It is almost as if TRX is held for sale or waiting for someone to swoop. What price would you put on the business, 3-4p? Worth holding on for that then, having passed the chance to exit at 1.7p.

theprior 22 Jan 2020

Interesting RNS Don’t panic, TRX will come good, they’ll sort out the financing, who knows, maybe another placing? But need a higher sp first. TP

Ripley94 22 Jan 2020

Interesting RNS Yes theprior financing always the problem i have found to my cost. SXX last one…i was so sure that was a good idea !! ( before last years collapse in price ) I can not recall who warned me about financing some years back on that one,some broker or annalist i must of rang about something . wish i had heeded that.

theprior 22 Jan 2020

Interesting RNS Numbers look good but the market doesn’t like the uncertainty still prevailing around future financing. Break even is close but still eludes them. Funding intact to end April but still working on post April funding. That’s the bugbear. But, TRX, is still a good company with a world class range of products. Value will out in the end! I had a little top up this morning but missed the low spot. Watch this space. Still a long way to go imho TP

Ripley94 22 Jan 2020

Interesting RNS TRX… XXXX Appears the numbers did not go down well theprior I see the low was when i was posting shortly after looking at it 0.6p on 11th November. A big pull back again 15% to 1.31p … what do you think ?

theprior 14 Jan 2020

Interesting RNS Closed at 1.70 today, +36%. What will it do when the numbers start coming through? TP

theprior 06 Jan 2020

Interesting RNS Prepare for take off 1.20 today, had a top up at .96recently. How’s that? Onwards and upwards. Value will out

theprior 05 Dec 2019

Interesting RNS Bit of movement this morning (+10%) after a quiet period. Is this the start of the recovery? Hope so! Topped up quite a bit whilst it was sub 1p. TP

theprior 20 Nov 2019

Interesting RNS I think we’ll have to wait for the next results (or maybe the ones after that) before we can get a clear picture of likely future profitability. With TRX (as with anything medical/pharmaceutical) progress is slow as new products and markets are explored. They are still, even now, early stage. The real change will only happen a long way down the road. Meanwhile, it’s a case of staying alive. I suspect I’d cap were a bit miffed that TRX had drawn down cash knowing they were in imminent danger of breaching the covenants. (May also be why the CFO has departed). If you believe the company has a future it’s worth hanging on at these levels or even buying more ! Gods luck to all invested TP

marktime1231 20 Nov 2019

Interesting RNS Oh dear, TRX has lost its newly instated CFO Mike Barker after just three months “for personal reasons”. I wonder if those reasons include the way he handled renegotiation with MidCap Finance leaving TRX at risk of running out of cash in 3-4 months, or the idea that he is not likely to be able to attract replacement funding. It doesn’t sound as if the board have a C level replacement in mind, which must leave TRX highly vulnerable to being snapped up on the cheap. But who might fancy the gamble?

marktime1231 14 Nov 2019

Interesting RNS theprior: Break even can’t be far away now You may be right, in which case why would MidCap withdraw funds? The 2018 report included an outlook of nearing “sustainable profitability” in 2019 but that does not seem at all likely from the reported numbers. I must have missed the rns saying a second production shift was up and running, investment in which would surely increase costs ahead of revenues. The update 4 weeks ago said … The increase in throughput is now expected to become available during Q4 2019 Even growing sales at the 33% headline rate it would take another year or two to make first profit. But the update 4 weeks ago said revenue for 2019 will be below current market consensus by approximately 15% to 20%, with a corresponding reduction in margin Take those comments together and overall losses may have widened this year rather than narrowed. You obviously read things differently though, and you are not alone looking at trading today. You suggest they might raise funds with a listing of new shares but that would be difficult to sell even at 1.09p unless there are really good hard 2019 numbers to report next February. Indeed I may have made a slight error in my analysis, it would not be the first time, but I will continue to err on the side of caution in this case. Good luck to you though.

Ripley94 14 Nov 2019

Interesting RNS TRX… XXXX Hi marktime1231 Not that i know anything about successful trading but as you have responded to me . That is what i would do . I give no advise. I was last year maybe ? praised for grabbing Halo cheap … kept it… ended badly . I hope this is different .